Mr Mat Daniel

Honorary Consultant Lecturer, Otology and Hearing group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham

Consultant Otorhinolaryngologist with specialist interest in Paediatric ENT
Honorary Consultant Lecturer, Otology and Hearing group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham
Adjunct Senior Lecturer, Medical Engineering Design and Innovation Centre, Cork Institute of Technology

Following undergraduate study at The University of Birmingham, Mat trained in ENT in the East Midlands, and completed a fellowship in Paediatric Otorhinolaryngology in Sydney. He is a Fellow of the Royal Colleges of Surgeons of England and Edinburgh, holds postgraduate qualifications in Management and Medical Education, and is a Fellow of the Higher Education Academy. He has recently completed his PhD at The University of Nottingham, entitled "Otitis media with effusion: Current treatment, new understanding of its aetiopathogenesis and a novel therapeutic approach".

In addition to peer-reviewed publications and presentations, his research has won multiple prizes, including those awarded by the Royal Society of Medicine, Otorhinolaryngologic Research Society, British Association for Paediatric Otorhinolaryngology, and American Society of Pediatric Otolaryngology.

Expertise summary

Mat's main research interests have focused on the role of bacteria and biofilms in OME, and the treatment of biofilms with antibiotics. Biofilms are groups of bacteria living together surrounded by slime and attached to a surface. They are present in the middle ear of children with OME, and they are known to be difficult to kill with antibiotics. His current work is therefore investigating novel approaches to eradicate biofilms, by using antibiotic pellets that would release antibiotics over a period of several weeks t the site of infection, and then disintegrate of their own accord once they are no longer needed. This research is an interdisciplinary collaboration between the NIHR Nottingham Hearing BRU, Nottingham University's Division of Otorhinolaryngology (with Professor Birchall), Biomaterials-Related Infection Group at the Division of Orthopaedic and Accident Surgery (Dr Bayston), and the School of Pharmacy (Professor Shakesheff). Mat has also studied outcomes of grommet surgery and adenoidectomy as part of the TARGET (‘Trial of Alternative Regimens in Glue Ear Treatment’) trial for OME, investigated the effect that NICE guidelines on OME management have had on clinical practice, and collaborated with the Study of Environment on Aboriginal Resilience and Childhood Health.

Mat uses his clinical knowledge, combined with research experience, to undertake both basic science and clinical research, with the primary aims of translating laboratory work into direct patient benefit.