BSA lunch and learn eSeminar: Cell transplantation therapy and age related hearing loss

Members of the general public are welcome to attend our seminars. However space is limited so if you would like to attend, please ring Sandra Smith at least 24 hours prior to the seminar on 0115 823 2634 to reserve a place. If Sandra Smith is unavailable contact Jan Kelly on 0115 823 2617 or contact reception on 0115 823 2600.

08 November 2012

Presenter(s): Dr David Furness
Time: 12.30 – 13.30
Location: NHBRU, Meeting Room 1


As the causes of age-related hearing loss have become better understood, a number of possible targets for cell replacement or regeneration have been identified. The major effort has generally been expended in replacing the sensory hair cells of the organ of Corti to restore hearing.  However, it may well be equally fruitful to target other cells such as the spiral ganglion neurones that transmit the neural signal to the higher auditory pathway, or the spiral ligament fibrocytes that contribute to the homeostatic mechanism that maintains the endocochlear potential and ultimate ensure the survival of the hair cells themselves. I will review these possible targets, focussing particularly on the fibrocytes and their contribution, as well as ways they may be replaced to prevent age-related hearing loss.